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Squidbillies is an animated television series about the Cuylers, an impoverished family of anthropomorphic hillbilly mud squids living in the Appalachian region of Georgia's mountains. The show is produced by Williams Street Studios for the Adult Swim programming block of Cartoon Network and premiered on October 16, 2005. It is written by Dave Willis, co-creator of Aqua Teen Hunger Force, and Jim Fortier, previously of The Brak Show, both of whom worked on the Adult Swim series Space Ghost Coast to Coast. The animation is done by Awesome Incorporated, with background design by Ben Prisk.

From the creator of "BoJack Horseman" comes this animated comedy about a family over time, following siblings from childhood to adulthood and back again.

Orel is an 11-year-old boy who loves church. His unbridled enthusiasm for piousness and his misinterpretation of religious morals often lead to disastrous results, including self-mutilation and crack addiction. No matter how much trouble he gets into, his reverence always keeps him cheery.

Alien supervillain Killface wants to destroy Earth. Billionaire playboy Xander Crews realizes he can make more money if he stops him. Who will win?

Social worker Mark Lilly helps new citizens—both human and "other"—begin the process of adapting to life in the Big Apple, but his coworkers, demonic bureaucrat Twayne, drunken wizard Leonard Powers, surly law enforcement head Frank Grimes & his girlfriend, Callie, don't make it easy.